Here’s how designer Sabyasachi created Deepika Padukone, Ranveer Singh’s wedding outfits – watch videos

Deepika Padukone and Ranveer Singh in their outfits were a sight to behold at their Italian wedding. Fashion designer Sabyasachi Mukherjee shares how their wedding attires were made. Check out the videos

Ranveer Singh, Deepika Padukone

Ranveer Singh, Deepika Padukone  |  Photo Credit: Instagram

Deepika Padukone and Ranveer Singh’s Italy wedding photos have left an indelible mark on our minds. With candid expressions, the couple’s Konkani and Sindhi wedding traditions spoke volumes about their closeness towards their families. While Deepika was a sight to behold in her dazzling red lehenga for their Sindhi wedding, Ranveer took a U-turn from his unconventional style and looked like the perfect groom for his ladylove.

Fashion designer Sabyasachi Mukherjee, whose outfits were the highlight in the grand DeepVeer wedding, shared a glimpse of how both Deepika and Ranveer’s attires were made. He shared snippets from behind-the-scenes about how intricately Deepika’s lehenga was designed, hand-stitched and beautifully embroidered.

On the other hand, Ranveer’s wedding sherwani which was hand-knitted with golden buttons as fixtures and beautifully stitched dupatta with gold work, exhibited the designer’s love for revival in Indian traditional fashion. With decadent, monotone and simple ensembles, Ranveer and Deepika’s Sabyasachi creations have given several couples some wedding outfit ideas.

Check out the making of Ranveer’s sherwani and Deepika’s lehenga in these videos…

(Also read: 5 things you need to know about Deepika Padukone, Ranveer Singh’s Mumbai wedding reception – details inside)

After DeepVeer’s Bangalore wedding reception on November 21, the couple has hosted another wedding reception today for Ranveer’s family and later they will hold a party to celebrate with their industry friends. The Mumbai reception today is expected to commence at 8 pm that will take place at the Grand Hyatt Hotel.

The couple married in Villa del Balbianello at Lake Como in Italy. Instead of a horse, Ranveer chose to arrive with his baraat on a seaplane since the Villa was surrounded by the water body.


UH scientists: Everyone should be alarmed if Chinese researcher actually gene-edited babies

It’s the baby news that sparked outrage in the scientific community.

A Chinese scientist claims to have created the world’s first genetically-modified babies by altering the DNA of human embryos. He Jiankui says the twin girls are now genetically resistant to HIV.

Steven Ward, director of UH’s Institute for Biogenesis Research, says he was appalled to learn of the news.

“It is hard to see it as other than a stunt. It really takes away the credibility of all the scientists who are trying to do good with this,” he said.

Dr. Jennifer Doudna, a pioneer of the CRISPR gene editing technology and a Hilo High graduate, also spoke out against the experiment that didn’t follow scientific protocols and has not been verified.

“I think it’s a break from what was recommended by the report released by the Image result for UH scientists: Everyone should be alarmed if Chinese researcher actually gene-edited babiesNational Academy of Science last year, 2017, that encouraged an open and transparent approach to any clinical use of human embryo editing,” she said.

Doudna spoke at UH Hilo and the UH Cancer Center in September, warning of the technology’s misuse.

“People forging ahead to make CRSPR babies that’s a little creepy to me,” said Doudna, at UH Hilo.

“I feel a strong responsibility that it’s not just to make a first, but also make it an example,” He Jiankui told the Associated Press. He added: “Society will decide what to do next.”

Jesse Owens is an assistant professor at UH’s Institute for Biogenesis Research and is trying to make CRISPR technology safer. He says gene therapy could have medical benefits for adults, but not on human embryos.

“If you have a child that child’s child will have that same mutation and that child’s child, it will go on forever. That’s the line that nobody crosses,” he said.


Outrage Over Human Gene Editing Will Fade Fast

It’s too soon to know whether a Chinese researcher who claims to have successfully edited the genomes of newly born twins is telling the truth. But if he is, and if the girls turn out to be healthy and normal, it heralds a significant change in the scientific and ethical status of human gene editing. The outrage might not last long.

The consensus in the scientific community now is that human gene editing is medically dangerous and ethically wrong. Both of those beliefs are susceptible to changing, almost as fast as science is capable of progressing.

And, interestingly, the two main concerns about gene editing using the Crispr-Cas 9 system are almost diametrically opposed, logically speaking.

The first worry is that Crispr technology, while cheap and powerful, isn’t reliable enough for use in humans. Specifically, the concern is that changes in one gene that has been “knocked out” and replaced with another could have unforeseen and harmful effects elsewhere in the genome.

Called “off-target” effects, such unintended modifications are rare but not unheard of in Crispr experiments in mice. When it comes to humans, the worry goes, an intended mutation that is beneficial or even lifesaving could turn out to have serious, permanent negative effects elsewhere.

The second worry is that Crispr editing of the human genome will work all too well. That could lead to parents seeking to have designer babies, offspring whose genomes have been edited so that they will be more athletic or more attractive or more intelligent.

The ethical concerns there range from the obvious (it seems too much like eugenics) to the more subtle (it could enhance class differences between those with access to the technology and those without).

Then there’s the fact that gene editing isn’t restricted to that one child. Crispr genetic mutations are passed on to the next generation, whether for good or for ill.

These scientific and ethical concerns are serious. But they can change fast.

Consider the off-target effects. This worry is based on empirical science: either there is a meaningful probability of dangerous off-target mutations, or there isn’t. If children like the twins who have been reportedly modified are born and live healthy, normal lives, then scientific worries about off-target effects will begin to recede.

As an editorial in Nature Medicine pointed out last summer, all acts of sexual reproduction carry a background probability of spontaneous mutation — that’s why evolution is possible. If the rate of off-target effects is lower than that of natural mutation, scientists and regulators may come to consider it to be tolerable.

That leaves the designer-babies worry — and there are a couple of reasons to predict that it, too, may fade.

To begin with, designing taller or smarter babies is not a realistic possibility in the foreseeable future. Most observable human features are associated with hundreds of genetic mutations, not just one or two. One leading study on height found that 697 genetic variants accounted for one-fifth of the difference among people. It isn’t realistic to use Crispr to knock out and replace those 697 genes to achieve a possible 20 percent gain in height.

Other examples of human variability, such as intelligence, would be even harder to change with current editing techniques. We can’t even produce a consistent definition of intelligence, much less identify its genetic determinants.

As the public gradually realizes that designer babies aren’t a very realistic option, the ethical worry about producing them is likely to fade.

What will remain is the strong ethical value of protecting future generations from debilitating disease. The reported Chinese human editing case was unnecessary, because there are other, simpler ways of protecting a fetus from contracting HIV from a paternal donor. But plenty of other diseases can be avoided only by genetic mutation.

If and when it becomes scientifically safe to proceed with human gene editing, the legitimate ethical concern about designer babies is likely to be outweighed by the ethical imperative to avoid disease, and to enable parents to reproduce who might otherwise not have been able to do so.

Over time, the ethical question will cease to be whether it is permissible to use gene editing to prevent disease. Instead, ethicists will be asking whether it is ethically permissible not to make interventions that would avoid human pain and suffering.

All this will take time — possibly as long as a decade, depending on how many scientists break the current norms and how well their patients do. But if the science works, expect the ethical norms to follow. Forty years ago, ethicists fretted about in vitro fertilization. Today, the practice seems ethically unproblematic or even attractive to the public in most countries.


What Deepika Padukone’s wedding saree designer has to say about Sabyasachi credit controversy

Deepika Padukone's wedding saree designer speaks out about Sabyasachi controversy.

Deepika Padukone ooked like a vision in all of her wedding looks. While earlier it was believed that Sabyasachi had designed and conceptualised all of her wedding looks, it was later revealed that that was not the case.

Deepika’s gorgeous red and gold saree was bought by her and her mother from a very famous silk store in Bengaluru called The House Of Angadi.

Sabyasachi and his team, who had earlier taken credit for dressing up Deepika on her Konkani wedding day ‘head to toe’ later issued an apology after the original designer K Radharaman contacted famous fashion journalist Shefalee Vasudev about the same and she brought the matter to light.

Sabyasachi issued a written apology and gave credits to the original label immediately.

Deepika’s saree for the Bengaluru reception was also designed by K Radharaman.

Anyway, a long time after the controversy took place, the man behind the gorgeous designs finally decided to speak about it. Here is what he said:

“I do not and never did have any intention of being critical of Sabyasachi Mukherjee or anyone else. I do not have any negative sentiment towards anyone and we did thank him publicly on social media for giving credit to us after we pointed the error to him.”

He continued:

“That said, when I was informed that another design label had claimed credit for my work, I felt obligated to speak up on behalf of the entire design community of which we are all a part of.”


Stop designer baby experiments

The dystopian Brave New World of designer babies may be upon us, courtesy of Chinese scientist He Jiankui.

The physics expert, who has no experience with human clinical trials, announced that twin girls had been born from embryos that he “gene-edited” in an attempt to increase their resistance to HIV.

He Jiankui’s experiment to genetically modify twin girls using a gene-editing tool has been met with worldwide condemnation.
He Jiankui’s experiment to genetically modify twin girls using a gene-editing tool has been met with worldwide condemnation.  (Mark Schiefelbein / THE ASSOCIATED PRESS)

And that is not good news.

In fact, his announcement on Monday — bizarrely made on YouTube — was met with worldwide condemnation, including from HIV researchers and some 120 Chinese scientists who denounced his work as “madness.”

Elsewhere, scientists criticized the secret and unjustifiable testing of a hypothesis when experts have no idea what the repercussions and possible mutations will be for these children, Lulu and Nana, never mind future generations as the altered DNA is passed on.

But what is known is scary enough. People without a normal CCR5 gene, the one He edited, have a higher risk of contracting other viruses, such as West Nile, and dying from the flu. And the twins’ risk of cancer could increase dramatically.

This experiment could also lead to the slippery slope of trying to create superhuman designer babies, a path that the late Stephen Hawking warned could lead to the end of “unimproved humans.”

“The Pandora’s Box has been opened, but we may still have a chance to close it before it is irreparable,” Chinese scientists said in a joint statement.

Their words should be heeded in laboratories around the world.


Urban Zen Celebrates Designer and Artist Robert Lee Morris

Having worked hand in hand with Robert Lee Morris for years on jewelry with her own brands, Donna Karan always knew that she wanted to do something special for the artist within her Urban Zen space. “This reminds me of everything we’ve done together and now he’s taking it into another dimension and I see even more reasons to do it together,” she expressed.

Karan’s whole idea of Urban Zen is, “past, present and future” (through preserving culture and future education); she celebrated the works of Lee Morris’ as such through an intimate gathering of his latest sculptural works, displayed within the  Greenwich space among photographs by Jimmy Nelson, sculptures by Karan’s late husband Stephan Weiss, and handmade accessories, home decor, textiles, clothing and more from artisans around the world.

“This is an official launch of the latest sculpture collection,” Lee Morris proclaimed. ”I’ve been making them and making them and making them and they piled up, so I had no more room in my studio. I happened to come to a birthday party for Stan Herman here [at Urban Zen] and Donna said, “What have you been doing?” and I showed her the pictures and she went, ‘I want them here, immediately.’ So from that point, which was only about two months ago, we scrambled to get all this together.

While sculpture is something Lee Morris has always done, it was never a major focus until the last year or two.

“Now I consider myself a sculptor,” he stated, “I’ve been a jewelry designer, but my main focus now is sculpting. It’s not wearable stuff, but things that look like they have the jewelry touch somehow.there’s a sensitivity, a fragility.”

In the past, Lee Morris had shown, and sold, larger sculptural works in Donna Karan’s Madison Avenue store, as well as in some galleries, but he saw more movement with his smaller brass works with home decor appeal. The sculptor explained that each piece takes about two days, or “one very furious day,” where he cuts and hammers until his hands can no longer hold the works-in-progress. Each piece, from the more affordable “sails” or larger “artichoke fire” pieces indeed hold the appeal and allure of his work in jewelry.

A range of his productions was shown Tuesday night and will be available for purchase throughout Urban Zen’s upcoming Holiday Marketplace — smaller “sails” sculptures and a small assortment of jewelry starting individually for $350 to $5,000 and ranging up to $12,500. Works that are perfect for the holidays and Christmas lists, according to Lee Morris. “I would really love it if someone would give me a sculpture like this. (So one-of-a-kind.) Especially if it’s someone you already own and appreciate their work.”